| 03 Jun 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Charlotte FC | — | → |
| 31 May 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Colorado Rapids | — | → |
| 29 May 2023 | Major League Soccer (USA) | Nashville SC | - : - | Columbus Crew SC | — | → |
| 20 May 2023 | Major League Soccer (USA) | FC Cincinnati | - : - | Columbus Crew SC | — | → |
| 17 May 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | LA Galaxy | — | → |
| 13 May 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Orlando City SC | — | → |
| 29 Apr 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Inter Miami CF | — | → |
| 22 Apr 2023 | Major League Soccer (USA) | Charlotte FC | - : - | Columbus Crew SC | — | → |
| 15 Apr 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | New England Revolution | — | → |
| 08 Apr 2023 | Major League Soccer (USA) | D.C. United | - : - | Columbus Crew SC | — | → |
| 01 Apr 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Real Salt Lake | — | → |
| 25 Mar 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | Atlanta United FC | — | → |
| 18 Mar 2023 | Major League Soccer (USA) | New York Red Bulls | - : - | Columbus Crew SC | — | → |
| 12 Mar 2023 | Major League Soccer (USA) | Toronto FC | - : - | Columbus Crew SC | — | → |
| 05 Mar 2023 | Major League Soccer (USA) | Columbus Crew SC | - : - | D.C. United | — | → |
| 26 Feb 2023 | Major League Soccer (USA) | Philadelphia Union | - : - | Columbus Crew SC | — | → |
| 09 Oct 2022 | Major League Soccer (USA) | Orlando City SC | - : - | Columbus Crew SC | — | → |
| 01 Oct 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | New York Red Bulls | — | → |
| 18 Sept 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Portland Timbers | — | → |
| 14 Sept 2022 | Major League Soccer (USA) | Inter Miami CF | - : - | Columbus Crew SC | — | → |
| 09 Sept 2022 | Major League Soccer (USA) | Montreal Impact | - : - | Columbus Crew SC | — | → |
| 03 Sept 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Chicago Fire | — | → |
| 31 Aug 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Inter Miami CF | — | → |
| 27 Aug 2022 | Major League Soccer (USA) | FC Cincinnati | - : - | Columbus Crew SC | — | → |
| 21 Aug 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Atlanta United FC | — | → |
| 14 Aug 2022 | Major League Soccer (USA) | Colorado Rapids | - : - | Columbus Crew SC | — | → |
| 06 Aug 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | New York City FC | — | → |
| 03 Aug 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Montreal Impact | — | → |
| 30 Jul 2022 | Major League Soccer (USA) | Charlotte FC | - : - | Columbus Crew SC | — | → |
| 23 Jul 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | New England Revolution | — | → |
| 17 Jul 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | FC Cincinnati | — | → |
| 14 Jul 2022 | Major League Soccer (USA) | D.C. United | - : - | Columbus Crew SC | — | → |
| 10 Jul 2022 | Major League Soccer (USA) | Chicago Fire | - : - | Columbus Crew SC | — | → |
| 03 Jul 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Philadelphia Union | — | → |
| 29 Jun 2022 | Major League Soccer (USA) | Toronto FC | - : - | Columbus Crew SC | — | → |
| 26 Jun 2022 | Major League Soccer (USA) | Real Salt Lake | - : - | Columbus Crew SC | — | → |
| 18 Jun 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Charlotte FC | — | → |
| 28 May 2022 | Major League Soccer (USA) | Atlanta United FC | - : - | Columbus Crew SC | — | → |
| 21 May 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Los Angeles FC | — | → |
| 14 May 2022 | Major League Soccer (USA) | New York City FC | - : - | Columbus Crew SC | — | → |
| 07 May 2022 | Major League Soccer (USA) | New England Revolution | - : - | Columbus Crew SC | — | → |
| 30 Apr 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | D.C. United | — | → |
| 24 Apr 2022 | Major League Soccer (USA) | Sporting Kansas City | - : - | Columbus Crew SC | — | → |
| 16 Apr 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Orlando City SC | — | → |
| 09 Apr 2022 | Major League Soccer (USA) | Philadelphia Union | - : - | Columbus Crew SC | — | → |
| 02 Apr 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Nashville SC | — | → |
| 20 Mar 2022 | Major League Soccer (USA) | New York Red Bulls | - : - | Columbus Crew SC | — | → |
| 12 Mar 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Toronto FC | — | → |
| 05 Mar 2022 | Major League Soccer (USA) | San Jose Earthquakes | - : - | Columbus Crew SC | — | → |
| 26 Feb 2022 | Major League Soccer (USA) | Columbus Crew SC | - : - | Vancouver Whitecaps FC | — | → |