Fixtures (306)
| Date | Home | Score | Away | FT | HT | |
|---|---|---|---|---|---|---|
| 16 May 2021 | AZ Alkmaar | 5 – 0 | Heracles | H | 1–0 | → |
| 16 May 2021 | Feyenoord | 3 – 0 | Waalwijk | H | 2–0 | → |
| 16 May 2021 | Heerenveen | 1 – 2 | Sparta Rotterdam | A | 0–2 | → |
| 16 May 2021 | Twente | 3 – 2 | Den Haag | H | 2–2 | → |
| 16 May 2021 | Utrecht | 1 – 1 | PSV Eindhoven | D | 1–0 | → |
| 16 May 2021 | Vitesse | 1 – 3 | Ajax | A | 1–2 | → |
| 16 May 2021 | VVV Venlo | 0 – 4 | FC Emmen | A | 0–1 | → |
| 16 May 2021 | Willem II | 2 – 1 | For Sittard | H | 1–0 | → |
| 16 May 2021 | Zwolle | 1 – 0 | Groningen | H | 0–0 | → |
| 13 May 2021 | Ajax | 3 – 1 | VVV Venlo | H | 1–0 | → |
| 13 May 2021 | Den Haag | 1 – 4 | Willem II | A | 0–3 | → |
| 13 May 2021 | FC Emmen | 3 – 1 | Heerenveen | H | 1–0 | → |
| 13 May 2021 | For Sittard | 3 – 3 | Vitesse | D | 2–2 | → |
| 13 May 2021 | Groningen | 0 – 0 | AZ Alkmaar | D | 0–0 | → |
| 13 May 2021 | Heracles | 1 – 1 | Feyenoord | D | 0–0 | → |
| 13 May 2021 | PSV Eindhoven | 4 – 2 | Zwolle | H | 3–0 | → |
| 13 May 2021 | Sparta Rotterdam | 0 – 0 | Utrecht | D | 0–0 | → |
| 13 May 2021 | Waalwijk | 2 – 1 | Twente | H | 0–0 | → |
| 09 May 2021 | FC Emmen | 0 – 4 | Groningen | A | 0–1 | → |
| 09 May 2021 | Feyenoord | 0 – 3 | Ajax | A | 0–1 | → |
| 09 May 2021 | Zwolle | 0 – 1 | Den Haag | A | 0–1 | → |
| 09 May 2021 | Willem II | 0 – 2 | PSV Eindhoven | A | 0–1 | → |
| 08 May 2021 | Twente | 1 – 1 | Heracles | D | 0–0 | → |
| 08 May 2021 | Heerenveen | 0 – 0 | Utrecht | D | 0–0 | → |
| 08 May 2021 | AZ Alkmaar | 1 – 0 | For Sittard | H | 1–0 | → |
| 08 May 2021 | VVV Venlo | 3 – 3 | Waalwijk | D | 2–2 | → |
| 07 May 2021 | Sparta Rotterdam | 3 – 0 | Vitesse | H | 1–0 | → |
| 02 May 2021 | Den Haag | 3 – 2 | Feyenoord | H | 2–1 | → |
| 02 May 2021 | Ajax | 4 – 0 | FC Emmen | H | 1–0 | → |
| 02 May 2021 | Groningen | 1 – 2 | Sparta Rotterdam | A | 0–1 | → |
| 02 May 2021 | PSV Eindhoven | 2 – 2 | Heerenveen | D | 0–1 | → |
| 01 May 2021 | Heracles | 4 – 0 | VVV Venlo | H | 2–0 | → |
| 01 May 2021 | For Sittard | 3 – 0 | Twente | H | 1–0 | → |
| 01 May 2021 | Vitesse | 2 – 1 | Zwolle | H | 1–0 | → |
| 01 May 2021 | Waalwijk | 1 – 3 | AZ Alkmaar | A | 1–1 | → |
| 01 May 2021 | Utrecht | 3 – 2 | Willem II | H | 2–0 | → |
| 25 Apr 2021 | FC Emmen | 3 – 1 | Heracles | H | 0–0 | → |
| 25 Apr 2021 | Ajax | 2 – 0 | AZ Alkmaar | H | 0–0 | → |
| 25 Apr 2021 | Den Haag | 0 – 3 | For Sittard | A | 0–1 | → |
| 25 Apr 2021 | Feyenoord | 0 – 0 | Vitesse | D | 0–0 | → |
| 25 Apr 2021 | Twente | 1 – 2 | Utrecht | A | 1–0 | → |
| 24 Apr 2021 | Heerenveen | 0 – 2 | Zwolle | A | 0–1 | → |
| 24 Apr 2021 | PSV Eindhoven | 1 – 0 | Groningen | H | 0–0 | → |
| 24 Apr 2021 | Sparta Rotterdam | 2 – 0 | VVV Venlo | H | 1–0 | → |
| 23 Apr 2021 | Willem II | - : - | Waalwijk | — | undefined–undefined | → |
| 22 Apr 2021 | Ajax | - : - | Utrecht | — | undefined–undefined | → |
| 11 Apr 2021 | Utrecht | 1 – 2 | Feyenoord | A | 1–1 | → |
| 11 Apr 2021 | Groningen | 0 – 2 | Heerenveen | A | 0–0 | → |
| 11 Apr 2021 | VVV Venlo | 0 – 2 | PSV Eindhoven | A | 0–1 | → |
| 11 Apr 2021 | Waalwijk | 0 – 1 | Ajax | A | 0–1 | → |
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